Technology

One platform. Every decision point.

A single, guideline-complete molecular assay that runs on the real-time PCR hardware most labs already own — delivering NGS-class sensitivity and 100% specificity, from tissue or blood.

The platform, in four ideas

Accurate. Fast. Agile. Smart.

Accurate

Sensitivity that beats NGS.

Median LoD₉₅ 0.3% VAF in blood; <3% VAF in tissue. 100% specificity across every guideline gene. In head-to-head validation: 97/100% PPA/NPA vs NGS.

Fast

Next-day report.

A clinician-ready result the day after the sample reaches the lab. Reports in as little as 34 hours — even from a QNS sample.

Agile

Tissue or blood. One panel.

Same 11-gene guideline-complete panel runs on FFPE tissue or 10 mL of plasma. Repeatable for serial monitoring — turning a snapshot into a molecular timeline.

Smart

DNA + RNA together.

Both nucleic acids in a single workflow — every actionable driver, whether it's a mutation or a fusion. Plus resistance intelligence over time.

The ONCO X assay family

Five assays. One platform. Every decision point.

Each ONCO X test is a purpose-built application of the same core chemistry — tuned to the indication, the sample type, and the clinical question. All five run on the same QuantStudio™ 5 hardware, so a lab that adopts one can eventually run them all.

PulmoSmart · Live

PulmoSmart

The workhorse NSCLC panel on FFPE tissue. 11 guideline genes, 114 variants, DNA and RNA together from a single sample. 5–7 day turnaround, 100% specificity, ~1% failure rate versus the ~25% NGS norm. Built for the tissue blocks Indian oncologists actually work with.

PulmoSmart Prime · Live

PulmoSmart Prime

The same guideline-complete 11-gene NSCLC panel — delivered in 2 days on a fast-track workflow. For fast-progressing disease, fragile patients, and cases where the oncologist needs the molecular answer before the next clinic visit.

LiquiSmart · Live · Cancer Resistance Test

LiquiSmart

Ultra-sensitive ctDNA testing from a single 10 mL blood draw. Median LoD₉₅ 0.3% VAF, 100% specificity, 34-hour actionable reports — even from QNS samples that failed NGS. Repeatable for serial monitoring, so resistance becomes visible before imaging shows progression: EGFR T790M/C797S, ALK G1202R, MET and HER2 bypass amplification.

OcuriaSmart · Launching soon

OcuriaSmart

A urine- and tissue-based molecular assay for bladder cancer — designed for both non-muscle-invasive (NMIBC) and muscle-invasive (MIBC) disease. Covers FGFR3, TERT promoter, TP53, PIK3CA and RAS hotspots for early detection, recurrence surveillance and treatment stratification. Same PCR platform, same next-day economics.

ColoSmart · Launching soon

ColoSmart

A guideline-complete panel for metastatic colorectal cancer — KRAS, NRAS, BRAF V600E, PIK3CA, HER2 amplification and MSI status in a single reflex-friendly workflow. Designed to answer the anti-EGFR and immunotherapy questions in one run, from FFPE tissue or plasma, on the QuantStudio your lab already runs.

On the roadmap

Our own NGS platform — in months.

PCR gives us speed and lab-friendly economics for the tests that matter most, most days. But some indications — deep multi-gene profiling, tumor-informed MRD, comprehensive genomic profiling — need next-generation sequencing depth.

ONCO X is bringing its own NGS platform to Indian oncology in the coming months — engineered for local throughput, local pricing, and the same rigor of clinical validation.

Read the announcement
Independently validated

Tested in the labs that set the standard.

  • Reagents developed under ISO 13485 manufacturing
  • Assay clinically validated at a CLIA-certified, CAP-accredited laboratory
  • Independently validated by ONCO X for India · NABL accredited laboratory
  • Consistent performance across MD Anderson, UPenn, Medical College of Wisconsin & Fred Hutch
  • 77 clinical samples analysed across sites — including pleural effusions, FNAs and FNA washes
  • Peer-reviewed publications in Frontiers in Oncology, Journal of Liquid Biopsy, and Translational Lung Cancer Research